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Oxycodone ameliorates the inflammatory response induced by lipopolysaccharide in primary microglia

BACKGROUND: Activation of microglia participates in a wide range of pathophysiological processes in the central nervous system. Some studies reported that oxycodone (6-deoxy-7,8-dehydro-14-hydroxy-3-O-methyl-6oxomorphine) could inhibit the overactivation of glial cells in rats’ spinal cords. In the...

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Detalles Bibliográficos
Autores principales: Ye, Jishi, Yan, Hong, Xia, Zhongyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018850/
https://www.ncbi.nlm.nih.gov/pubmed/29950892
http://dx.doi.org/10.2147/JPR.S160659