Glucocorticoid receptor-mediated amygdalar metaplasticity underlies adaptive modulation of fear memory by stress

Glucocorticoid receptor (GR) is crucial for signaling mediated by stress-induced high levels of glucocorticoids. The lateral nucleus of the amygdala (LA) is a key structure underlying auditory-cued fear conditioning. Here, we demonstrate that genetic disruption of GR in the LA (LAGRKO) resulted in a...

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Detalles Bibliográficos
Autores principales: Inoue, Ran, Abdou, Kareem, Hayashi-Tanaka, Ayumi, Muramatsu, Shin-ichi, Mino, Kaori, Inokuchi, Kaoru, Mori, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019067/
https://www.ncbi.nlm.nih.gov/pubmed/29941090
http://dx.doi.org/10.7554/eLife.34135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019067/
https://www.ncbi.nlm.nih.gov/pubmed/29941090
http://dx.doi.org/10.7554/eLife.34135

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