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Glucocorticoid receptor-mediated amygdalar metaplasticity underlies adaptive modulation of fear memory by stress
Glucocorticoid receptor (GR) is crucial for signaling mediated by stress-induced high levels of glucocorticoids. The lateral nucleus of the amygdala (LA) is a key structure underlying auditory-cued fear conditioning. Here, we demonstrate that genetic disruption of GR in the LA (LAGRKO) resulted in a...
Autores principales: | Inoue, Ran, Abdou, Kareem, Hayashi-Tanaka, Ayumi, Muramatsu, Shin-ichi, Mino, Kaori, Inokuchi, Kaoru, Mori, Hisashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019067/ https://www.ncbi.nlm.nih.gov/pubmed/29941090 http://dx.doi.org/10.7554/eLife.34135 |
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