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B cells are capable of independently eliciting rapid reactivation of encephalitogenic CD4 T cells in a murine model of multiple sclerosis

Recent success with B cell depletion therapies has revitalized efforts to understand the pathogenic role of B cells in Multiple Sclerosis (MS). Using the adoptive transfer system of experimental autoimmune encephalomyelitis (EAE), a murine model of MS, we have previously shown that mice in which B c...

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Detalles Bibliográficos
Autores principales: Parker Harp, Chelsea R., Archambault, Angela S., Sim, Julia, Shlomchik, Mark J., Russell, John H., Wu, Gregory F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019098/
https://www.ncbi.nlm.nih.gov/pubmed/29944721
http://dx.doi.org/10.1371/journal.pone.0199694