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Genome Mining of the Marine Actinomycete Streptomyces sp. DUT11 and Discovery of Tunicamycins as Anti-complement Agents

Marine actinobacteria are potential producers of various secondary metabolites with diverse bioactivities. Among various bioactive compounds, anti-complement agents have received great interest for drug discovery to treat numerous diseases caused by inappropriate activation of the human complement s...

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Detalles Bibliográficos
Autores principales: Xu, Xiao-Na, Chen, Liang-Yu, Chen, Chao, Tang, Ya-Jie, Bai, Feng-Wu, Su, Chun, Zhao, Xin-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019454/
https://www.ncbi.nlm.nih.gov/pubmed/29973921
http://dx.doi.org/10.3389/fmicb.2018.01318