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Topoisomerase II Poisons for Glioblastoma; Existing Challenges and Opportunities to Personalize Therapy
Despite advances in surgery, radiotherapy, and chemotherapy, glioblastoma (GBM) remains a malignancy with poor prognosis. The molecular profile of GBM is diverse across patients, and individual responses to therapy are highly variable. Yet, patients diagnosed with GBM are treated with a rather unifo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019456/ https://www.ncbi.nlm.nih.gov/pubmed/29988316 http://dx.doi.org/10.3389/fneur.2018.00459 |