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Topoisomerase II Poisons for Glioblastoma; Existing Challenges and Opportunities to Personalize Therapy

Despite advances in surgery, radiotherapy, and chemotherapy, glioblastoma (GBM) remains a malignancy with poor prognosis. The molecular profile of GBM is diverse across patients, and individual responses to therapy are highly variable. Yet, patients diagnosed with GBM are treated with a rather unifo...

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Detalles Bibliográficos
Autores principales:	Mehta, Amol, Awah, Chidiebere U., Sonabend, Adam M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019456/ https://www.ncbi.nlm.nih.gov/pubmed/29988316 http://dx.doi.org/10.3389/fneur.2018.00459

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