Deletion of Specific Sphingolipids in Distinct Neurons Improves Spatial Memory in a Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is characterized by progressive neurodegeneration and a concomitant loss of synapses and cognitive abilities. Recently, we have proposed that an alteration of neuronal membrane lipid microdomains increases neuronal resistance toward amyloid-β stress in cultured neurons and p...

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Detalles Bibliográficos
Autores principales: Herzer, Silke, Hagan, Cassidy, von Gerichten, Johanna, Dieterle, Vanessa, Munteanu, Bogdan, Sandhoff, Roger, Hopf, Carsten, Nordström, Viola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019486/
https://www.ncbi.nlm.nih.gov/pubmed/29973867
http://dx.doi.org/10.3389/fnmol.2018.00206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019486/
https://www.ncbi.nlm.nih.gov/pubmed/29973867
http://dx.doi.org/10.3389/fnmol.2018.00206

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