A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework

BACKGROUND: There is considerable evidence that many complex traits have a partially shared genetic basis, termed pleiotropy. It is therefore useful to consider integrating genome-wide association study (GWAS) data across several traits, usually at the summary statistic level. A major practical chal...

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Detalles Bibliográficos
Autores principales: LeBlanc, Marissa, Zuber, Verena, Thompson, Wesley K., Andreassen, Ole A., Frigessi, Arnoldo, Andreassen, Bettina Kulle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019513/
https://www.ncbi.nlm.nih.gov/pubmed/29940862
http://dx.doi.org/10.1186/s12864-018-4859-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019513/
https://www.ncbi.nlm.nih.gov/pubmed/29940862
http://dx.doi.org/10.1186/s12864-018-4859-7

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