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A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework
BACKGROUND: There is considerable evidence that many complex traits have a partially shared genetic basis, termed pleiotropy. It is therefore useful to consider integrating genome-wide association study (GWAS) data across several traits, usually at the summary statistic level. A major practical chal...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019513/ https://www.ncbi.nlm.nih.gov/pubmed/29940862 http://dx.doi.org/10.1186/s12864-018-4859-7 |