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SNPrune: an efficient algorithm to prune large SNP array and sequence datasets based on high linkage disequilibrium

BACKGROUND: High levels of pairwise linkage disequilibrium (LD) in single nucleotide polymorphism (SNP) array or whole-genome sequence data may affect both performance and efficiency of genomic prediction models. Thus, this warrants pruning of genotyping data for high LD. We developed an algorithm,...

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Detalles Bibliográficos
Autores principales: Calus, Mario P. L., Vandenplas, Jérémie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019535/
https://www.ncbi.nlm.nih.gov/pubmed/29940846
http://dx.doi.org/10.1186/s12711-018-0404-z