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Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs
Loss of cystic fibrosis transmembrane conductance regulator (CFTR) function causes cystic fibrosis (CF), predisposing the lungs to chronic infection and inflammation. In young infants with CF, structural airway defects are increasingly recognized before the onset of significant lung disease, which s...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019641/ https://www.ncbi.nlm.nih.gov/pubmed/29467455 http://dx.doi.org/10.1038/s41374-018-0026-7 |