Cargando…

Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs

Loss of cystic fibrosis transmembrane conductance regulator (CFTR) function causes cystic fibrosis (CF), predisposing the lungs to chronic infection and inflammation. In young infants with CF, structural airway defects are increasingly recognized before the onset of significant lung disease, which s...

Descripción completa

Detalles Bibliográficos
Autores principales: Meyerholz, David K., Stoltz, David A., Gansemer, Nick D., Ernst, Sarah E., Cook, Daniel P., Strub, Matthew D., LeClair, Erica N., Barker, Carrie K., Adam, Ryan J., Leidinger, Mariah R., Gibson-Corley, Katherine N., Karp, Philip H., Welsh, Michael J., McCray, Paul B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019641/
https://www.ncbi.nlm.nih.gov/pubmed/29467455
http://dx.doi.org/10.1038/s41374-018-0026-7