Potential role for histone deacetylation in chronic diazepam‐induced downregulation of α1‐GABA(A) receptor subunit expression

Corroborating evidence indicate that the downregulation of GABA(A) receptor subunit expression may underlie tolerance to the anticonvulsant and anxiolytic actions of benzodiazepine (BZ) ligands that act as full allosteric modulators (FAMs) of GABA actions at a variety of GABA(A) receptor subtypes. W...

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Detalles Bibliográficos
Autores principales: Auta, James, Gatta, Eleonora, Davis, John M., Pandey, Subhash C., Guidotti, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019704/
https://www.ncbi.nlm.nih.gov/pubmed/29951207
http://dx.doi.org/10.1002/prp2.416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019704/
https://www.ncbi.nlm.nih.gov/pubmed/29951207
http://dx.doi.org/10.1002/prp2.416

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