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Interference with KCTD9 inhibits NK cell activation and ameliorates fulminant liver failure in mice

BACKGROUND: Potassium channel tetramerisation domain containing 9 (KCTD9), a member of KCTD family with a DNA-like pentapeptide repeat domain, was found to be increased particularly in NK cells of patients with HBV-induced acute-on-chronic liver failure (HBV-ACLF) and experimental viral fulminant he...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoping, Zhu, Lin, Zhou, Yaoyong, Shi, Aichao, Wang, Hongwu, Han, Meifang, Wan, Xiaoyang, Kilonzo, Semvua Bukheti, Luo, Xiaoping, Chen, Tao, Ning, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019787/
https://www.ncbi.nlm.nih.gov/pubmed/29940856
http://dx.doi.org/10.1186/s12865-018-0256-x