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A computational approach to identify cellular heterogeneity and tissue-specific gene regulatory networks

BACKGROUND: The heterogeneity of cells across tissue types represents a major challenge for studying biological mechanisms as well as for therapeutic targeting of distinct tissues. Computational prediction of tissue-specific gene regulatory networks may provide important insights into the mechanisms...

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Detalles Bibliográficos
Autores principales: Jambusaria, Ankit, Klomp, Jeff, Hong, Zhigang, Rafii, Shahin, Dai, Yang, Malik, Asrar B., Rehman, Jalees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019795/
https://www.ncbi.nlm.nih.gov/pubmed/29940845
http://dx.doi.org/10.1186/s12859-018-2190-6