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A computational approach to identify cellular heterogeneity and tissue-specific gene regulatory networks
BACKGROUND: The heterogeneity of cells across tissue types represents a major challenge for studying biological mechanisms as well as for therapeutic targeting of distinct tissues. Computational prediction of tissue-specific gene regulatory networks may provide important insights into the mechanisms...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019795/ https://www.ncbi.nlm.nih.gov/pubmed/29940845 http://dx.doi.org/10.1186/s12859-018-2190-6 |