Gene expression profile and cancer-associated pathways linked to progesterone receptor isoform a (PRA) predominance in transgenic mouse mammary glands

BACKGROUND: Progesterone receptor (PR) is expressed from a single gene as two isoforms, PRA and PRB. In normal breast human tissue, PRA and PRB are expressed in equimolar ratios, but isoform ratio is altered during malignant progression, usually leading to high PRA:PRB ratios. We took advantage of a...

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Detalles Bibliográficos
Autores principales: Carlini, María José, Recouvreux, María Sol, Simian, Marina, Nagai, Maria Aparecida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019805/
https://www.ncbi.nlm.nih.gov/pubmed/29940887
http://dx.doi.org/10.1186/s12885-018-4550-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019805/
https://www.ncbi.nlm.nih.gov/pubmed/29940887
http://dx.doi.org/10.1186/s12885-018-4550-z

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