Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways

BACKGROUND: Cancer cells require increased levels of nutrients such as amino acids to sustain their rapid growth. In particular, leucine and glutamine have been shown to be important for growth and proliferation of some breast cancers, and therefore targeting the primary cell-surface transporters th...

Descripción completa

Detalles Bibliográficos
Autores principales: van Geldermalsen, Michelle, Quek, Lake-Ee, Turner, Nigel, Freidman, Natasha, Pang, Angel, Guan, Yi Fang, Krycer, James R., Ryan, Renae, Wang, Qian, Holst, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019833/
https://www.ncbi.nlm.nih.gov/pubmed/29940911
http://dx.doi.org/10.1186/s12885-018-4599-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019833/
https://www.ncbi.nlm.nih.gov/pubmed/29940911
http://dx.doi.org/10.1186/s12885-018-4599-8

Ejemplares similares