Dual blockade of PI3K and MEK in combination with radiation in head and neck cancer

BACKGROUND AND PURPOSE: In this study we have combined fractionated radiation treatment (RT) with two molecular targeted agents active against key deregulated signaling pathways in head and neck cancer. MATERIALS AND METHODS: We used two molecularly characterized, low passage HNSCC cell lines of dif...

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Detalles Bibliográficos
Autores principales: Blas, Kevin, Wilson, Thomas G., Tonlaar, Nathan, Galoforo, Sandra, Hana, Alaa, Marples, Brian, Wilson, George D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019866/
https://www.ncbi.nlm.nih.gov/pubmed/30014041
http://dx.doi.org/10.1016/j.ctro.2018.04.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019866/
https://www.ncbi.nlm.nih.gov/pubmed/30014041
http://dx.doi.org/10.1016/j.ctro.2018.04.003

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