Cargando…

Suppression of chloride voltage-gated channel 3 expression increases sensitivity of human glioma U251 cells to cisplatin through lysosomal dysfunction

The mechanism of cisplatin resistance is complex. Previous studies have indicated that chloride voltage-gated channel 3 (CLCN3) is associated with drug resistance; however, the mechanisms are not fully understood. Therefore, the present study explored the involvement of CLCN3 in cisplatin resistance...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yihe, Zhou, Lei, Zhang, Juanjuan, Zhang, Lichao, Yan, Xiaoyu, Su, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019884/
https://www.ncbi.nlm.nih.gov/pubmed/29963152
http://dx.doi.org/10.3892/ol.2018.8736