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Overexpressing modified human TRβ1 suppresses the proliferation of breast cancer MDA-MB-468 cells

A number of studies have indicated that thyroid hormone receptor β1 (TRβ1) functions as a tumor suppressor. TRs mediate transcriptional responses through a highly conserved DNA-binding domain (DBD). A novel rat TRβ isoform (rTRβΔ) was previously identified, in which a novel exon, N (108 bp), is loca...

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Detalles Bibliográficos
Autores principales: Peng, Xiaoxiang, Zhang, Yangyang, Sun, Yanli, Wang, Lujuan, Song, Wei, Li, Qian, Zhao, Ronglan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019938/
https://www.ncbi.nlm.nih.gov/pubmed/29963146
http://dx.doi.org/10.3892/ol.2018.8764