Activation of mTORC1 in chondrocytes does not affect proliferation or differentiation, but causes the resting zone of the growth plate to become disordered

There are several pitfalls associated with research based on transgenic mice. Here, we describe our interpretation and analysis of mTORC1 activation in growth plate chondrocytes and compare these to a recent publication (Yan et al., Nature Communications 2016, 7:11151). Both laboratories employed TS...

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Detalles Bibliográficos
Autores principales: Newton, Phillip T., Xie, Meng, Medvedeva, Ekaterina V., Sävendahl, Lars, Chagin, Andrei S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020113/
https://www.ncbi.nlm.nih.gov/pubmed/29955624
http://dx.doi.org/10.1016/j.bonr.2018.02.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020113/
https://www.ncbi.nlm.nih.gov/pubmed/29955624
http://dx.doi.org/10.1016/j.bonr.2018.02.006

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