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Structure and dynamics of a human myelin protein P2 portal region mutant indicate opening of the β barrel in fatty acid binding proteins

BACKGROUND: Myelin is a multilayered proteolipid sheath wrapped around selected axons in the nervous system. Its constituent proteins play major roles in forming of the highly regular membrane structure. P2 is a myelin-specific protein of the fatty acid binding protein (FABP) superfamily, which is a...

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Detalles Bibliográficos
Autores principales: Laulumaa, Saara, Nieminen, Tuomo, Raasakka, Arne, Krokengen, Oda C., Safaryan, Anushik, Hallin, Erik I., Brysbaert, Guillaume, Lensink, Marc F., Ruskamo, Salla, Vattulainen, Ilpo, Kursula, Petri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020228/
https://www.ncbi.nlm.nih.gov/pubmed/29940944
http://dx.doi.org/10.1186/s12900-018-0087-2