Treatment of voluminous and complicated superficial slow-flow vascular malformations with sirolimus (PERFORMUS): protocol for a multicenter phase 2 trial with a randomized observational-phase design

BACKGROUND: Slow-flow superficial vascular malformations (VMs) are rare congenital anomalies that can be responsible for pain and functional impairment. Currently, we have no guidelines for their management, which can involve physical bandages, sclerotherapy, surgery, anti-inflammatory or anti-coagu...

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Detalles Bibliográficos
Autores principales: Maruani, Annabel, Boccara, Olivia, Bessis, Didier, Guibaud, Laurent, Vabres, Pierre, Mazereeuw-Hautier, Juliette, Barbarot, Sébastien, Chiaverini, Christine, Blaise, Sophie, Droitcourt, Catherine, Mallet, Stéphanie, Martin, Ludovic, Lorette, Gérard, Woillard, Jean-Baptiste, Jonville-Bera, Annie-Pierre, Rollin, Jérome, Gruel, Yves, Herbreteau, Denis, Goga, Dominique, le Touze, Anne, Leducq, Sophie, Gissot, Valérie, Morel, Baptiste, Tavernier, Elsa, Giraudeau, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020321/
https://www.ncbi.nlm.nih.gov/pubmed/29945674
http://dx.doi.org/10.1186/s13063-018-2725-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020321/
https://www.ncbi.nlm.nih.gov/pubmed/29945674
http://dx.doi.org/10.1186/s13063-018-2725-1

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