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CpG island composition differences are a source of gene expression noise indicative of promoter responsiveness

BACKGROUND: Population phenotypic variation can arise from genetic differences between individuals, or from cellular heterogeneity in an isogenic group of cells or organisms. The emergence of gene expression differences between genetically identical cells is referred to as gene expression noise, the...

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Detalles Bibliográficos
Autores principales: Morgan, Michael D., Marioni, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020341/
https://www.ncbi.nlm.nih.gov/pubmed/29945659
http://dx.doi.org/10.1186/s13059-018-1461-x