Cargando…

CD44 glycoprotein in cancer: a molecular conundrum hampering clinical applications

CD44 is a heavily glycosylated membrane receptor playing a key role in cell adhesion, signal transduction and cytoskeleton remodelling. It is also one of the most studied glycoproteins in cancer, frequently explored for stem cell identification, and associated with chemoresistance and metastasis. Ho...

Descripción completa

Detalles Bibliográficos
Autores principales: Azevedo, Rita, Gaiteiro, Cristiana, Peixoto, Andreia, Relvas-Santos, Marta, Lima, Luís, Santos, Lúcio Lara, Ferreira, José Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020424/
https://www.ncbi.nlm.nih.gov/pubmed/29983670
http://dx.doi.org/10.1186/s12014-018-9198-9