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CD44 glycoprotein in cancer: a molecular conundrum hampering clinical applications
CD44 is a heavily glycosylated membrane receptor playing a key role in cell adhesion, signal transduction and cytoskeleton remodelling. It is also one of the most studied glycoproteins in cancer, frequently explored for stem cell identification, and associated with chemoresistance and metastasis. Ho...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020424/ https://www.ncbi.nlm.nih.gov/pubmed/29983670 http://dx.doi.org/10.1186/s12014-018-9198-9 |