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Distribution and change of peroxynitrite in the guinea pig cochlea following noise exposure

Nitric oxide (NO)-mediated pathology depends on the formation of reactive intermediates, such as the peroxynitrite (ONOO(−)). ONOO(−) can nitrate free tyrosine and tyrosine residues of proteins. Therefore, increases in tyrosine nitration reflect the amount of ONOO(−) produced by oxidative stress. Th...

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Detalles Bibliográficos
Autores principales: Han, Wei-Ju, Shi, Xiao-Rui, Nuttall, Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020447/
https://www.ncbi.nlm.nih.gov/pubmed/29963305
http://dx.doi.org/10.3892/br.2018.1107