Therapy-induced stress response is associated with downregulation of pre-mRNA splicing in cancer cells

BACKGROUND: Abnormal pre-mRNA splicing regulation is common in cancer, but the effects of chemotherapy on this process remain unclear. METHODS: To evaluate the effect of chemotherapy on slicing regulation, we performed meta-analyses of previously published transcriptomic, proteomic, phosphoproteomic...

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Detalles Bibliográficos
Autores principales: Anufrieva, Ksenia S., Shender, Victoria О., Arapidi, Georgij P., Pavlyukov, Marat S., Shakhparonov, Michail I., Shnaider, Polina V., Butenko, Ivan O., Lagarkova, Maria A., Govorun, Vadim M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020472/
https://www.ncbi.nlm.nih.gov/pubmed/29950180
http://dx.doi.org/10.1186/s13073-018-0557-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020472/
https://www.ncbi.nlm.nih.gov/pubmed/29950180
http://dx.doi.org/10.1186/s13073-018-0557-y

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