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Therapy-induced stress response is associated with downregulation of pre-mRNA splicing in cancer cells

BACKGROUND: Abnormal pre-mRNA splicing regulation is common in cancer, but the effects of chemotherapy on this process remain unclear. METHODS: To evaluate the effect of chemotherapy on slicing regulation, we performed meta-analyses of previously published transcriptomic, proteomic, phosphoproteomic...

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Detalles Bibliográficos
Autores principales:	Anufrieva, Ksenia S., Shender, Victoria О., Arapidi, Georgij P., Pavlyukov, Marat S., Shakhparonov, Michail I., Shnaider, Polina V., Butenko, Ivan O., Lagarkova, Maria A., Govorun, Vadim M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020472/ https://www.ncbi.nlm.nih.gov/pubmed/29950180 http://dx.doi.org/10.1186/s13073-018-0557-y

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