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Immunotherapy with Native Molecule rather than Hypoallergenic Variant of Pru p 3, the Major Peach Allergen, Shows Beneficial Effects in Mice

BACKGROUND: The use of hypoallergenic derivatives is considered beneficial to promote the safety and efficacy of allergen-specific immunotherapy. We aimed to assess the efficacy of reduced and alkylated (R/A) Pru p 3, a hypoallergenic folding variant of the major peach allergen, in subcutaneous immu...

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Detalles Bibliográficos
Autores principales: Rodriguez, Maria J., Wangorsch, Andrea, Gomez, Francisca, Schülke, Stefan, Torres, Maria J., Vieths, Stefan, Scheurer, Stephan, Toda, Masako, Mayorga, Cristobalina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020533/
https://www.ncbi.nlm.nih.gov/pubmed/30009186
http://dx.doi.org/10.1155/2018/3479185