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The Nicotinic Cholinergic Pathway Contributes to Retinal Neovascularization in a Mouse Model of Retinopathy of Prematurity

PURPOSE: To investigate the role of nicotinic acetylcholine receptors (nAChRs) in retinal vascular development and ischemia-induced retinal neovascularization (NV). METHODS: The expression of nAChR subtypes and VEGF signaling pathway components was assessed in mice with and without oxygen-induced is...

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Detalles Bibliográficos
Autores principales: Hackett, Sean F., Seidel, Christopher, Abraham, Sheena, Chadha, Rishi, Fortmann, Seth D., Campochiaro, Peter A., Cooke, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020715/
https://www.ncbi.nlm.nih.gov/pubmed/28241318
http://dx.doi.org/10.1167/iovs.16-20670