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Equal Expansion of Endogenous Transplant-Specific Regulatory T Cell and Recruitment Into the Allograft During Rejection and Tolerance

Despite numerous advances in the definition of a role for regulatory T cells (Tregs) in facilitating experimental transplantation tolerance, and ongoing clinical trials for Treg-based therapies, critical issues related to the optimum dosage, antigen-specificity, and Treg-friendly adjunct immunosuppr...

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Detalles Bibliográficos
Autores principales: Young, James S., Yin, Dengping, Vannier, Augustin Georges Louis, Alegre, Maria-Luisa, Chong, Anita S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020780/
https://www.ncbi.nlm.nih.gov/pubmed/29973932
http://dx.doi.org/10.3389/fimmu.2018.01385