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Enhanced Mutant Compensates for Defects in Rhodopsin Phosphorylation in the Presence of Endogenous Arrestin-1

We determined the effects of different expression levels of arrestin-1-3A mutant with enhanced binding to light-activated rhodopsin that is independent of phosphorylation. To this end, transgenic mice that express mutant rhodopsin with zero, one, or two phosphorylation sites, instead of six in the W...

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Detalles Bibliográficos
Autores principales: Samaranayake, Srimal, Song, Xiufeng, Vishnivetskiy, Sergey A., Chen, Jeannie, Gurevich, Eugenia V., Gurevich, Vsevolod V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020793/
https://www.ncbi.nlm.nih.gov/pubmed/29973866
http://dx.doi.org/10.3389/fnmol.2018.00203