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Enhanced Mutant Compensates for Defects in Rhodopsin Phosphorylation in the Presence of Endogenous Arrestin-1
We determined the effects of different expression levels of arrestin-1-3A mutant with enhanced binding to light-activated rhodopsin that is independent of phosphorylation. To this end, transgenic mice that express mutant rhodopsin with zero, one, or two phosphorylation sites, instead of six in the W...
Autores principales: | Samaranayake, Srimal, Song, Xiufeng, Vishnivetskiy, Sergey A., Chen, Jeannie, Gurevich, Eugenia V., Gurevich, Vsevolod V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020793/ https://www.ncbi.nlm.nih.gov/pubmed/29973866 http://dx.doi.org/10.3389/fnmol.2018.00203 |
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