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Long-Term Stress Disrupts the Structural and Functional Integrity of GABAergic Neuronal Networks in the Medial Prefrontal Cortex of Rats

Clinical and experimental data suggest that fronto-cortical GABAergic deficits contribute to the pathophysiology of major depressive disorder (MDD). To further test this hypothesis, we used a well characterized rat model for depression and examined the effect of stress on GABAergic neuron numbers an...

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Detalles Bibliográficos
Autores principales: Czéh, Boldizsár, Vardya, Irina, Varga, Zsófia, Febbraro, Fabia, Csabai, Dávid, Martis, Lena-Sophie, Højgaard, Kristoffer, Henningsen, Kim, Bouzinova, Elena V., Miseta, Attila, Jensen, Kimmo, Wiborg, Ove
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020798/
https://www.ncbi.nlm.nih.gov/pubmed/29973870
http://dx.doi.org/10.3389/fncel.2018.00148