Reactive oxygen species inhibit catalytic activity of peptidylarginine deiminase

Protein citrullination catalysed by peptidylarginine deiminase (PAD) may play an important pathogenic role in several chronic inflammatory diseases and malignancies. PAD2, PAD4, and citrullinated proteins are found in the synovium of rheumatoid arthritis patients. PAD activity is dependent on calciu...

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Detalles Bibliográficos
Autores principales: Damgaard, Dres, Bjørn, Mads Emil, Jensen, Peter Østrup, Nielsen, Claus Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021033/
https://www.ncbi.nlm.nih.gov/pubmed/28933232
http://dx.doi.org/10.1080/14756366.2017.1368505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021033/
https://www.ncbi.nlm.nih.gov/pubmed/28933232
http://dx.doi.org/10.1080/14756366.2017.1368505

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