A MFS-like plasma membrane transporter required for Leishmania virulence protects the parasites from iron toxicity

Iron is essential for many cellular processes, but can generate highly toxic hydroxyl radicals in the presence of oxygen. Therefore, intracellular iron accumulation must be tightly regulated, by balancing uptake with storage or export. Iron uptake in Leishmania is mediated by the coordinated action...

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Detalles Bibliográficos
Autores principales: Laranjeira-Silva, Maria Fernanda, Wang, Wanpeng, Samuel, Tamika K., Maeda, Fernando Y., Michailowsky, Vladimir, Hamza, Iqbal, Liu, Zhongchi, Andrews, Norma W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021107/
https://www.ncbi.nlm.nih.gov/pubmed/29906288
http://dx.doi.org/10.1371/journal.ppat.1007140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021107/
https://www.ncbi.nlm.nih.gov/pubmed/29906288
http://dx.doi.org/10.1371/journal.ppat.1007140

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