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METTL3-mediated m(6)A modification is required for cerebellar development

N(6)-methyladenosine (m(6)A) RNA methylation is the most abundant modification on mRNAs and plays important roles in various biological processes. The formation of m(6)A is catalyzed by a methyltransferase complex including methyltransferase-like 3 (METTL3) as a key factor. However, the in vivo func...

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Detalles Bibliográficos
Autores principales: Wang, Chen-Xin, Cui, Guan-Shen, Liu, Xiuying, Xu, Kai, Wang, Meng, Zhang, Xin-Xin, Jiang, Li-Yuan, Li, Ang, Yang, Ying, Lai, Wei-Yi, Sun, Bao-Fa, Jiang, Gui-Bin, Wang, Hai-Lin, Tong, Wei-Min, Li, Wei, Wang, Xiu-Jie, Yang, Yun-Gui, Zhou, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021109/
https://www.ncbi.nlm.nih.gov/pubmed/29879109
http://dx.doi.org/10.1371/journal.pbio.2004880