Cryptococcus neoformans urease affects the outcome of intracellular pathogenesis by modulating phagolysosomal pH

Cryptococcus neoformans is a facultative intracellular pathogen and its interaction with macrophages is a key event determining the outcome of infection. Urease is a major virulence factor in C. neoformans but its role during macrophage interaction has not been characterized. Consequently, we analyz...

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Detalles Bibliográficos
Autores principales: Fu, Man Shun, Coelho, Carolina, De Leon-Rodriguez, Carlos M., Rossi, Diego C. P., Camacho, Emma, Jung, Eric H., Kulkarni, Madhura, Casadevall, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021110/
https://www.ncbi.nlm.nih.gov/pubmed/29906292
http://dx.doi.org/10.1371/journal.ppat.1007144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021110/
https://www.ncbi.nlm.nih.gov/pubmed/29906292
http://dx.doi.org/10.1371/journal.ppat.1007144

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