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Survivin antagonizes chemotherapy-induced cell death of colorectal cancer cells

Irinotecan (CPT-11) and oxaliplatin (L-OHP) are among the most frequently used drugs against colorectal tumors. Therefore, it is important to define the molecular mechanisms that these agents modulate in colon cancer cells. Here we demonstrate that CPT-11 stalls such cells in the G(2)/M phase of the...

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Detalles Bibliográficos
Autores principales: Rauch, Anke, Carlstedt, Annemarie, Emmerich, Claudia, Mustafa, Al-Hassan M., Göder, Anja, Knauer, Shirley K., Linnebacher, Michael, Heinzel, Thorsten, Krämer, Oliver H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021236/
https://www.ncbi.nlm.nih.gov/pubmed/29963241
http://dx.doi.org/10.18632/oncotarget.25600