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Survivin antagonizes chemotherapy-induced cell death of colorectal cancer cells
Irinotecan (CPT-11) and oxaliplatin (L-OHP) are among the most frequently used drugs against colorectal tumors. Therefore, it is important to define the molecular mechanisms that these agents modulate in colon cancer cells. Here we demonstrate that CPT-11 stalls such cells in the G(2)/M phase of the...
Autores principales: | Rauch, Anke, Carlstedt, Annemarie, Emmerich, Claudia, Mustafa, Al-Hassan M., Göder, Anja, Knauer, Shirley K., Linnebacher, Michael, Heinzel, Thorsten, Krämer, Oliver H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021236/ https://www.ncbi.nlm.nih.gov/pubmed/29963241 http://dx.doi.org/10.18632/oncotarget.25600 |
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