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Real-time methylation-specific PCR for the evaluation of methylation status of MGMT gene in glioblastoma
The methylation status of the O6-methylguanine-DNA methyltransferase (MGMT) gene is a strong predictor for the efficacy of temozolomide chemotherapy and survival periods. However, the correlation between the extent of methylation and the difference in survival times has not been fully clarified. Sim...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021237/ https://www.ncbi.nlm.nih.gov/pubmed/29963232 http://dx.doi.org/10.18632/oncotarget.25543 |