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The rabbit as an orthologous small animal model for APOBEC3A oncogenesis

APOBEC3 are cytidine deaminases that convert cytidine to uridine residues. APOBEC3A and APOBEC3B enzymes able to target genomic DNA are involved in oncogenesis of a sizeable proportion of human cancers. While the APOBEC3 locus is conserved in mammals, it encodes from 1–7 genes. APOBEC3A is conserved...

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Detalles Bibliográficos
Autores principales: Laude, Hélène C., Caval, Vincent, Bouzidi, Mohamed S., Li, Xiongxiong, Jamet, Florence, Henry, Michel, Suspène, Rodolphe, Wain-Hobson, Simon, Vartanian, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021247/
https://www.ncbi.nlm.nih.gov/pubmed/29963239
http://dx.doi.org/10.18632/oncotarget.25593