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Distinct Activities of Glycolytic Enzymes Identify Chronic Lymphocytic Leukemia Patients with a more Aggressive Course and Resistance to Chemo-Immunotherapy

A higher capacity to grow under hypoxic conditions can lead to a more aggressive behavior of tumor cells. Determining tumor activity under hypoxia may identify chronic lymphocytic leukemia (CLL) with aggressive clinical course and predict response to chemo-immunotherapy (CIT). A metabolic score was...

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Detalles Bibliográficos
Autores principales: Gdynia, Georg, Robak, Tadeusz, Kopitz, Jürgen, Heller, Anette, Grekova, Svetlana, Duglova, Katarina, Laukemper, Gloria, Heinzel-Gutenbrunner, Monika, Gutenbrunner, Cornelius, Roth, Wilfried, Ho, Anthony D., Schirmacher, Peter, Schmitt, Michael, Dreger, Peter, Sellner, Leopold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021262/
https://www.ncbi.nlm.nih.gov/pubmed/29884457
http://dx.doi.org/10.1016/j.ebiom.2018.05.030