A simulation study comparing slope model with mixed-model repeated measure to assess cognitive data in clinical trials of Alzheimer's disease

INTRODUCTION: In clinical trials of Alzheimer's disease, a mixed-model repeated measure approach often serves as the primary analysis when evaluating disease progression; a slope model may be secondary. METHODS: Longitudinal change from baseline (14-item version of Alzheimer's Disease Asse...

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Detalles Bibliográficos
Autores principales: Chen, Yun-Fei, Ni, Xiao, Fleisher, Adam S., Zhou, Wei, Aisen, Paul, Mohs, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021263/
https://www.ncbi.nlm.nih.gov/pubmed/29955651
http://dx.doi.org/10.1016/j.trci.2017.12.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021263/
https://www.ncbi.nlm.nih.gov/pubmed/29955651
http://dx.doi.org/10.1016/j.trci.2017.12.002

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