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Zinc-finger protein 471 suppresses gastric cancer through transcriptionally repressing downstream oncogenic PLS3 and TFAP2A

Zinc-finger protein 471 (ZNF471) was preferentially methylated in gastric cancer using promoter methylation array. The role of ZNF471 in human cancer is unclear. Here we elucidated the functional significance, molecular mechanisms and clinical impact of ZNF471 in gastric cancer. ZNF471 mRNA was sile...

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Detalles Bibliográficos
Autores principales: Cao, Lei, Wang, Shiyan, Zhang, Yanquan, Wong, Ka-Chun, Nakatsu, Geicho, Wang, Xiaohong, Wong, Sunny, Ji, Jiafu, Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021371/
https://www.ncbi.nlm.nih.gov/pubmed/29610526
http://dx.doi.org/10.1038/s41388-018-0220-5