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Zinc-finger protein 471 suppresses gastric cancer through transcriptionally repressing downstream oncogenic PLS3 and TFAP2A
Zinc-finger protein 471 (ZNF471) was preferentially methylated in gastric cancer using promoter methylation array. The role of ZNF471 in human cancer is unclear. Here we elucidated the functional significance, molecular mechanisms and clinical impact of ZNF471 in gastric cancer. ZNF471 mRNA was sile...
Autores principales: | Cao, Lei, Wang, Shiyan, Zhang, Yanquan, Wong, Ka-Chun, Nakatsu, Geicho, Wang, Xiaohong, Wong, Sunny, Ji, Jiafu, Yu, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021371/ https://www.ncbi.nlm.nih.gov/pubmed/29610526 http://dx.doi.org/10.1038/s41388-018-0220-5 |
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