Quiescence status of glioblastoma stem-like cells involves remodelling of Ca(2+) signalling and mitochondrial shape

Quiescence is a reversible cell-cycle arrest which allows cancer stem-like cells to evade killing following therapies. Here, we show that proliferating glioblastoma stem-like cells (GSLCs) can be induced and maintained in a quiescent state by lowering the extracellular pH. Through RNAseq analysis we...

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Detalles Bibliográficos
Autores principales: Aulestia, Francisco J., Néant, Isabelle, Dong, Jihu, Haiech, Jacques, Kilhoffer, Marie-Claude, Moreau, Marc, Leclerc, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021377/
https://www.ncbi.nlm.nih.gov/pubmed/29950651
http://dx.doi.org/10.1038/s41598-018-28157-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021377/
https://www.ncbi.nlm.nih.gov/pubmed/29950651
http://dx.doi.org/10.1038/s41598-018-28157-8

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