Comparative analysis of xenobiotic metabolising N-acetyltransferases from ten non-human primates as in vitro models of human homologues

Xenobiotic metabolising N-acetyltransferases (NATs) perform biotransformation of drugs and carcinogens. Human NAT1 is associated with endogenous metabolic pathways of cells and is a candidate drug target for cancer. Human NAT2 is a well-characterised polymorphic xenobiotic metabolising enzyme, modul...

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Detalles Bibliográficos
Autores principales: Tsirka, Theodora, Konstantopoulou, Maria, Sabbagh, Audrey, Crouau-Roy, Brigitte, Ryan, Ali, Sim, Edith, Boukouvala, Sotiria, Fakis, Giannoulis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021393/
https://www.ncbi.nlm.nih.gov/pubmed/29950659
http://dx.doi.org/10.1038/s41598-018-28094-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021393/
https://www.ncbi.nlm.nih.gov/pubmed/29950659
http://dx.doi.org/10.1038/s41598-018-28094-6

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